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Strict Standards: Non-static method PEAR::setErrorHandling() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/lib/functions.php on line 291
Strict Standards: Non-static method DB::connect() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/lib/functions.php on line 297
Strict Standards: Non-static method DB::parseDSN() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/includes/DB.php on line 520
Strict Standards: Non-static method DB::isError() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/includes/DB.php on line 557
Strict Standards: Non-static method DB::isError() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/lib/functions.php on line 298
Deprecated: Non-static method DB::isManip() should not be called statically, assuming $this from incompatible context in /home/avtor123/avtor123.nichost.ru/docs/includes/DB/mysql.php on line 297
Deprecated: mysql_escape_string(): This function is deprecated; use mysql_real_escape_string() instead. in /home/avtor123/avtor123.nichost.ru/docs/pages/showitem.php on line 5
Deprecated: Non-static method DB::isManip() should not be called statically, assuming $this from incompatible context in /home/avtor123/avtor123.nichost.ru/docs/includes/DB/mysql.php on line 297
Deprecated: Non-static method DB::isError() should not be called statically, assuming $this from incompatible context in /home/avtor123/avtor123.nichost.ru/docs/includes/DB/common.php on line 1153
Strict Standards: Non-static method DB::isError() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/pages/showitem.php on line 8 KMK:Ñîâðåìåííûå ìåòîäû èçó÷åíèÿ ñòðóêòóðû è ôóíêöèé èîííûõ êàíàëîâ., Ñîêîëîâà Î.Ñ. (îòâ. ðåä.).
Ñîâðåìåííûå ìåòîäû èçó÷åíèÿ ñòðóêòóðû è ôóíêöèé èîííûõ êàíàëîâ.
Èîííûå êàíàëû îáíàðóæåíû âî âñåõ òêàíÿõ æèâûõ îðãàíèçìîâ, ãäå îíè âûïîëíÿþò ñàìûå ðàçíîîáðàçíûå ôóíêöèè: ó÷àñòâóþò â ïîääåðæàíèè ïîòåíöèàëà ïîêîÿ è ðåïîëÿðèçàöèè ìåìáðàíû âîçáóäèìûõ êëåòîê, â îáåñïå÷åíèè ñåðäå÷íîé äåÿòåëüíîñòè, ïðè âûäåëåíèè íåéðîìåäèàòîðîâ, â ñåêðåöèè ãîðìîíîâ.  íåâîçáóäèìûõ êëåòêàõ èîííûå êàíàëû ó÷àñòâóþò â ïðîöåññàõ ïîääåðæàíèÿ áàëàíñà ýëåêòðîëèòîâ ïî÷å÷íûì ýïèòåëèåì, ãèïåðïîëÿðèçàöèè  è Ò êëåòîê ïðè èììóííîì îòâåòå, â ïðîöåññàõ ðåãóëÿöèè àïîïòîçà, êëåòî÷íîé äèôôåðåíöèðîâêè è ðîñòà è ìíîãèõ äðóãèõ ïðîöåññàõ.  ñâÿçè ñ òàêèì ðàçíîîáðàçèåì ôóíêöèé êàíàëîâ, äåôåêòû â èõ ðàáîòå âûçûâàþò ìíîæåñòâî ïàòîëîãè÷åñêèõ ñîñòîÿíèé: íåâðîëîãè÷åñêèå ðàññòðîéñòâà ñåðäå÷íóþ àðèòìèþ, ðàññåÿííûé ñêëåðîç, áîëåâîé ñèíäðîì è äð. Äîêàçàíà ñâÿçü íåêîòîðûõ êàíàëîâ ñ ïðîöåññàìè âîçíèêíîâåíèÿ è ðàçâèòèÿ ðàêîâûõ îïóõîëåé. Îäíèìè èç íàèáîëåå îñòðûõ ñîñòîÿíèé, âûçûâàåìûõ äåôåêòàìè êàëèåâûõ êàíàëîâ, ÿâëÿþòñÿ íàðóøåíèÿ ñåðäå÷íîãî ðèòìà è íåâðîëîãè÷åñêèå ðàññòðîéñòâà. Íàëè÷èå òî÷íûõ ïðîñòðàíñòâåííûõ ñòðóêòóð èîííûõ êàíàëîâ ÿâëÿåòñÿ ïðåäïîñûëêîé äëÿ ïîíèìàíèÿ ìåõàíèçìîâ èõ ôóíêöèîíèðîâàíèÿ íà àòîìíîì óðîâíå. Ìîíîãðàôèÿ ïîñâÿùåíà ñîâðåìåííûì ìåòîäàì èçó÷åíèÿ ñòðóêòóðû è ôóíêöèé èîííûõ êàíàëîâ, âêëþ÷àÿ ñòðóêòóðíûå, ýëåêòðîôèçèîëîãè÷åñêèå ìåòîäû è ìîëåêóëÿðíîå ìîäåëèðîâàíèå. - Ðåêîìåíäîâàíà äëÿ ñòóäåíòîâ ñòàðøèõ êóðñîâ ïî ñïåöèàëüíîñòè “áèîôèçèêà” è íàó÷íûõ ñîòðóäíèêîâ.
Deprecated: Non-static method DB::isManip() should not be called statically, assuming $this from incompatible context in /home/avtor123/avtor123.nichost.ru/docs/includes/DB/mysql.php on line 297
Deprecated: Non-static method DB::isError() should not be called statically, assuming $this from incompatible context in /home/avtor123/avtor123.nichost.ru/docs/includes/DB/common.php on line 1153
Strict Standards: Non-static method DB::isError() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/pages/showitem.php on line 68
Deprecated: Non-static method DB::isManip() should not be called statically, assuming $this from incompatible context in /home/avtor123/avtor123.nichost.ru/docs/includes/DB/mysql.php on line 297
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Strict Standards: Non-static method DB::isError() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/lib/functions.php on line 7
Deprecated: Non-static method DB::isManip() should not be called statically, assuming $this from incompatible context in /home/avtor123/avtor123.nichost.ru/docs/includes/DB/mysql.php on line 297
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Strict Standards: Non-static method DB::isError() should not be called statically in /home/avtor123/avtor123.nichost.ru/docs/lib/functions.php on line 18